In this time of dire need, Sepragen team is doing its part to solve the problem of COVID-19. We are providing equipment on an expedited basis to a company developing a vaccine for COVID- 19.

Chromatography Automated Systems

Chromatography Automated Systems

Multi-use Chromatography Systems

"Trusty"

Browse products

Single-use Chromatography Systems

"Adept"

Browse products

Continuous Chromatography Systems

"Fusion"

Browse products

Download Brochure

The QuantaSep is a family of revolutionary chromatography systems is designed to provide full automation of the purification process from laboratory to commercial production scales. These systems are powerful and flexible, yet easy to learn and use. They systems are compact and easily scalable and use the same design philosophy keeping your needs in mind. They are all run using the same easy to use, fully validated and 21cfr3 part 11 compliant software. They have the capability to automate all routine tasks including buffer dilution or buffer making depending on your needs, saving 100’s of hours in validating buffers and cutting down space requirements, time and overall cost of either development or cost of manufacturing. Clinical production can be scaled up rapidly in existing facilities without having to increase headcount and hence helping you take product into the market much quicker than currently possible. While all QuantaSep systems are equipped with UV, conductivity and pH detectors, they also contain two unique features to protect your product loss, 1) an active air trap and 2) a leak detector. The active air trap protects your column from air without increasing holdup volume and hence unnecessary dilution or gradient formation due to the holdup volumes of in a bubble trap. The leak detector another critical feature allows you to guarantee no loss of your expensive feed or buffers due to leaks being developed as a result of possible loose connections.

✖

The QuantaSep software has a unique Graphical HMI which allows you to control the system by clicking on valves and pumps in a manual mode or by building an automated protocol to run the system by simply filling a table by selecting the various parameter you require to run your process. Buffers and fractions can be easily switched by the preset parameters and gradients can be produced using the 2 pumps. All events, Alarms if any and switching parameters and chromatograms are logged.

✖

The QuantSep automatically produces batch records which include calibration information, method used in the run, the Chromatograms, the alarms and events log, security access and the data analysis report.

✖

✖

✖

✖

✖

Each of the QuantaSep family i.e., the Trustee, the Adept and the Fusion come in three formats, the “Standard”, the “Premier” and the “Elite” and can be further customized for your needs.

Standard QuantaSep without pre column sensors - Trusty

QantaSep Trusty (Standard)	Flow test Rate	#Pumps	#Inlets	#Fractions	#Columns	Gradient	Flow Direction - Fwd / Reverse / Bypass	Pre column Bubble Trap or Air Sensor / Auto Air Eject	Dual wavelength UV/ pH/ Conductivity Sensor	Pressure rating and Pressure sensor	Leak Sensor	Plumbing/manifolds/ fittings and piping/ tubing	Computer and cGMP compliant software
Trusty 100	0 - 100ml/min	2	6 + 6	10	3	Yes	Yes	Pre Column Auto Air Eject	Post column	6Bar	Yes	PP/PTFE	Yes
Trusty 1000	10ml/min - 1L/min	2	6 + 6	10	3	Yes	Yes	Pre Column Auto Air Eject	Post column	6Bar	Yes	PP/reinforced silicone rubber	Yes
Trusty 1000LX	0 - 100ml/min, 10ml/min - 1L/min	2* 2	(6 + 6 )*2	10*2	3*2	Yes	Yes	Pre Column Auto Air Eject	Post column	6Bar	Yes	PP/PTFE/reinforced silicone rubber	Yes
Trusty 1800	20ml/min - 1.8L/min	2	6 + 6	10	3	Yes	Yes	Pre Column Auto Air Eject	Post column	3Bar	Yes	PP/reinforced silicone rubber	Yes
Trusty 5000	50ml/min - 5L/min	2	4 + 4	6	1	Yes	Yes	Pre Column Auto Air Eject	Post column	3Bar	Yes	PP/reinforced silicone rubber	Yes
Trusty 10000	100 ml/min - 10L/min	2	4 + 4	6	1	Yes	Yes	Pre Column Auto Air Eject	Post column	3Bar	Yes	PP/reinforced silicone rubber	Yes
Trusty 30000	0.8L/min - 30L/min	2	4 + 4	4	1	Yes	Yes	Pre Column Auto Air Eject	Post column	6 Bar	Yes	PP	Yes
Trusty 60000	1.2L/min - 60L/min	2	4 + 4	4	1	Yes	Yes	Pre Column Auto Air Eject	Post column	6Bar	Yes	PP	Yes

Note:These systems have have Pre column detectors, Inline Buffer dilution or Precolumn Filters

All Systems have dual 280 nm and 254 nm UV detection

Quantasep software is 21 CFR Pt 11 compliant: Easy P&ID window for operation and display; manual and automated recipes; time, volume, bed volume and sensor driven step changes; event and alarm logs; chromatogram display, analysis and overlays; On-line calibration wizard; Journal; OPC-UA for connectivity; CSV

All systems are sanitary design and wetted materials are USP Grade VI and ADI free

Standard QuantaSep with Buffer Blending - Trusty Elite

QantaSep Buffer Blending - Trusty Elite (Standard)	Flow Rate	#Pumps	#Inlets	#Fractions	#Columns	Gradient	Flow Direction - Fwd / Reverse / Bypass	Pre column Bubble Trap or Air Sensor / Auto Air Eject	UV/ pH/ Conductivity Sensor	Flow Meter	Pre Column pH & conductivity	Buffer/pH/Conductivity Control	Pressure Rating and Sensor	Leak Sensor	Pre Column Filter	Plumbing/manifolds/ fittings and piping/ tubing	Computer and cGMP software
Trusty Elite 5000	500ml/min - 5L/min	5	3 x 5	6	1	Yes	Yes	Pre Column Auto Air Eject	Post column	6	2+2	Yes	3Bar	Yes	Yes	PP	Yes
Trusty Elite 10000	1L/min - 10L/min	5	3 x 5	6	1	Yes	Yes	Pre Column Auto Air Eject	Post column	6	2+2	Yes	3Bar	Yes	Yes	PP	Yes
Trusty Elite 30000	3L/min - 30L/min	5	3 x 5	4	1	Yes	Yes	Pre Column Auto Air Eject	Post column	6	2+2	Yes	4Bar	Yes	Yes	PP	Yes
Trusty Elite 60000	6L/min - 60L/min	5	3 x 5	4	1	Yes	Yes	Pre Column Auto Air Eject	Post column	6	2+2	Yes	4Bar	Yes	Yes	PP	Yes

Note: These systems have have Pre column detectors, Inline Buffer dilution or Precolumn Filters

All Systems have dual 280 nm and 254 nm UV detection

Quantasep software is 21 CFR Pt 11 compliant: Easy P&ID window for operation and display; manual and automated recipes; time, volume, bed volume and sensor driven step changes; event and alarm logs; chromatogram display, analysis and overlays; On-line calibration wizard; Journal; OPC-UA for connectivity; CSV

All systems are sanitary design and wetted materials are USP Grade VI and ADI free

QuantaSep with inline buffer dilution - Trusty Premier

QantaSep Inline Buffer Dillution - Trusty Premier (Standard)	Flow Rate	#Pumps	#Inlets	#Fractions	#Columns	Gradient	Flow Direction - Fwd / Reverse / Bypass	Pre column Bubble Trap or Air Sensor / Auto Air Eject	UV/ pH/ Conductivity Sensor	Flow Meter	Pre Column pH & conductivity	Inline Buffer dilution	Pressure Rating and Sensor	Leak Sensor	Pre Column Filter	Plumbing/manifolds/ fittings and piping/ tubing	Computer and cGMP software
Trusty Premier 5000	500ml/min - 5L/min	2	4 + 4	6	1	Yes	Yes	Pre Column Auto Air Eject	Post column	2	yes	Yes	3Bar	Yes	Yes	PP	Yes
Trusty Premier 10000	1L/min - 10L/min	2	4 + 4	6	1	Yes	Yes	Pre Column Auto Air Eject	Post column	2	yes	Yes	3Bar	Yes	Yes	PP	Yes
Trusty Premier 30000	3L/min - 30L/min	2	4 + 4	4	1	Yes	Yes	Pre Column Auto Air Eject	Post column	2	yes	Yes	6Bar	Yes	Yes	PP	Yes
Trusty Premier 60000	6L/min - 60L/min	2	4 + 4	4	1	Yes	Yes	Pre Column Auto Air Eject	Post column	2	yes	Yes	6Bar	Yes	Yes	PP	Yes

Standard Single Use QuantaSep-Adept

QuantaSep Adept (Single Use)	#Flow paths	Flow Rate ranges	#Pumps	#Inlets	#Fractions	#Columns	Flow Direction - Fwd / Reverse / Bypass	Pre column Bubble Trap or Air Sensor / Auto Air Eject	dual UV/ pH/ Conductivity Sensor	Pressure rating and Sensor	Leak Sensor	Tubing	Computer and cGMP software
Adept 300SU	2	0 - 100 ml/ min and 10-300 ml/min	2	6 + 6	6	1	Yes	Yes	Yes	3 bar	Yes	reinforced silicone rubber	Yes
Adept 3000SU	3	10 - 300 ml/min, 30 - 1500ml/min & 80 - 3000 ml/min	2	4 + 4	6	1	yes	Yes	Yes	3 bar	Yes	reinforced silicone rubber	Yes
Adept 10000SU	2	50 - 5000 ml/ min and 100-10000 ml/min	2	4 + 4	6	1	yes	Yes	Yes	3 bar	Yes	reinforced silicone rubber	Yes
Adept 16000SU	2	80 - 8000 ml/ min and 160-16000 ml/min	2	4 + 4	6	1	yes	Yes	Yes	3 bar	Yes	reinforced silicone rubber	Yes

All Systems have dual 280 nm and 254 nm UV detection

Quantasep software is 21 CFR Pt 11 compliant: Easy P&ID window for operation and display; manual and automated recipes; time, volume, bed volume and sensor driven step changes; event and alarm logs; chromatogram display, analysis and overlays; On-line calibration wizard; Journal; OPC-UA for connectivity; CSV

All systems are sanitary design and wetted materials are USP Grade VI and ADI free

Single Use QuantaSeps with inline buffer dilution- Adept Premier

Single Use QuantaSeps with inline buffer dilution- Adept Premier	# Interchangeable Flow paths	Flow Rate ranges	#Pumps	#Inlets	#Fractions	#Columns	Gradient	Flow Direction - Fwd / Reverse / Bypass	Pre column Bubble Trap or Air Sensor / Auto Air Eject	UV/ pH/ Conductivity Sensor	Flow Meter	Pre Column pH & conductivity	Inline Buffer dilution	Pressure Rating and pressure sensor	Leak Sensor	Pre Column Filter	Disposable tubing and manifolds and connectors	Computer and cGMP software
Adept Premier 300SU	2	10 - 100 ml/ min and 30-300 ml/min	2	6 + 6	6	1	Yes	Yes	Yes	Yes	2	Yes	Yes (unlimited flow rate range)	3 bar	Yes	yes	reinforced silicone rubber/ PP	Yes
Adept Premier 3000SU	3	30 - 300 ml/min, 300 - 1500ml/min & 800 - 3000 ml/min	2	4 + 4	6	1	Yes	Yes	Yes	Yes	2	Yes	Yes (unlimited flow rate range)	3 bar	Yes	yes	reinforced silicone rubber/ PP	Yes
Adept Premier 10000SU	2	500 - 5000 ml/ min and 1L-10L/min	2	4 + 4	6	1	Yes	Yes	Yes	Yes	2	Yes	Yes	3 bar	Yes	yes	reinforced silicone rubber/ PP	Yes
Adept Premier 16000SU	2	800 - 8000 ml/ min and 1.6L-16L/min	2	4 + 4	6	1	Yes	Yes	Yes	Yes	2	Yes	Yes	3 bar	Yes	yes	reinforced silicone rubber/ PP	Yes
All Systems have dual 280 nm and 254 nm UV detection

Note: These systems have have Pre column detectors, Inline Buffer dilution or Precolumn Filters

All Systems have dual 280 nm and 254 nm UV detection

Quantasep software is 21 CFR Pt 11 compliant: Easy P&ID window for operation and display; manual and automated recipes; time, volume, bed volume and sensor driven step changes; event and alarm logs; chromatogram display, analysis and overlays; On-line calibration wizard; Journal; OPC-UA for connectivity; CSV

All flowpaths are presterilized sanitary design and wetted materials are USP Grade VI and ADI free; column connectors are T/C; buffer connectors are quick connects

Single Use QuantaSeps with buffer blending - Adept Elite

Single Use QuantaSeps with buffer blending - Adept Elite	#Interchangeable Flow paths	Flow Rate ranges	#Pumps	#Inlets	#Fractions	#Columns	Gradient	Flow Direction - Fwd / Reverse / Bypass	Pre column Bubble Trap or Air Sensor / Auto Air Eject	Flow Meter	Pre Column pH & conductivity	UV/ pH/ Conductivity Sensor	Pre Column pH & conductivity control	Pressure Rating and pressure sensor	Leak Sensor	Pre Column Filter	Product contact disposable tubing and manifolds and connectors	Computer and cGMP software
Adept Elite 300SU	2	10 - 100 ml/ min and 30-300 ml/min	5	6 + 6	6	1	Yes	Yes	Yes	6	2+2	Yes	Yes	3 bar	Yes	yes	reinforced silicone rubber/ PP	Yes
Adept Elite 3000SU	3	30 - 300 ml/min, 300 - 1500ml/min & 800 - 3000 ml/min	5	4 + 4	6	1	Yes	Yes	Yes	6	2+2	Yes	Yes	3 bar	Yes	yes	reinforced silicone rubber/ PP	Yes
Adept Elite 10000SU	2	500 - 5000 ml/ min and 1L-10L/min	5	4 + 4	6	1	Yes	Yes	Yes	6	2+2	Yes	Yes	3 bar	Yes	yes	reinforced silicone rubber/ PP	Yes
Adept Elite 16000SU	2	800 - 8000 ml/ min and 1.6L-16L/min	5	4 + 4	6	1	Yes	Yes	Yes	6	2+2	Yes	Yes	3 bar	Yes	yes	reinforced silicone rubber/ PP	Yes

Note: These systems have have Pre column detectors, Inline Buffer dilution or Precolumn Filters

All Systems have dual 280 nm and 254 nm UV detection

Quantasep software is 21 CFR Pt 11 compliant: Easy P&ID window for operation and display; manual and automated recipes; time, volume, bed volume and sensor driven step changes; event and alarm logs; chromatogram display, analysis and overlays; On-line calibration wizard; Journal; OPC-UA for connectivity; CSV

All flowpaths are presterilized sanitary design and wetted materials are USP Grade VI and ADI free; column connectors are T/C; buffer connectors are quick connects

Continuous Chromatography Capture - Fusion

Continuous Chromatography Capture - Fusion		Flow Rate	#Pumps	#Inlets	#Fractions	#Columns	Flow Direction - Fwd / Reverse / Bypass	Pre column Bubble Trap or Air Sensor / Auto Air Eject	Post Column dual UV/ pH/ Conductivity Sensor	Pressure Sensor	Leak Sensor	Pre Column Filter
Fusion		10 - 100ml/ min SU & 30 - 300 ml/ min	2	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2	yes	no
Fusion 3000		10 - 300 ml/min, 30 - 1500ml/min & 80 - 3000 ml/min	2	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2	yes	no
Fusion 10000		50 - 5000 ml/ min and 100-10000 ml/min	2	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2	yes	no
Fusion 16000		80 - 8000 ml/ min and 160-16000 ml/min	2	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2	yes	no

Continuous Chromatography Capture inline buffer dilution - Fusion Premier

Continuous Chromatography Capture inline buffer dilution - Fusion Premier		Flow Rate	#Pumps	#Inlets	#Fractions	#Columns	Flow Direction - Fwd / Reverse / Bypass	Pre column Bubble Trap or Air Sensor / Auto Air Eject	UV/ pH/ Conductivity Sensor	Pre Column pH & conductivity	Inline Buffer dilution	Pressure Sensor	Leak Sensor	Pre Column Filter
Fusion Premier		10 - 100ml/ min SU & 30 - 300 ml/ min	2	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2 set	yes	1	yes	no
Fusion Premier 3000		10 - 300 ml/min, 30 - 1500ml/min & 80 - 3000 ml/min	2	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2 set	yes	1	yes	no
Fusion Premier 10000		50 - 5000 ml/ min and 100-10000 ml/min	2	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2 set	yes	1	yes	no
Fusion Premier 16000		80 - 8000 ml/ min and 160-16000 ml/min	2	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2 set	yes	1	yes	no

Continuous Chromatography Capture Buffer Blending - Fusion Elite

Continuous Chromatography Capture Buffer Blending - Fusion Elite		Flow Rate	#Pumps	#Inlets	#Fractions	#Columns	Flow Direction - Fwd / Reverse / Bypass	Pre column Bubble Trap or Air Sensor / Auto Air Eject	UV/ pH/ Conductivity Sensor	Pre Column pH & conductivity	Inline Buffer Blending	Pressure Sensor	Leak Sensor	Pre Column Filter
Fusion Elite		10 - 100ml/ min SU & 30 - 300 ml/ min	5	5 x 3	3x3	3	yes for each each column	yes for each column	3 set	2 set	yes	6	yes	no
Fusion Elite 3000		10 - 300 ml/min, 30 - 1500ml/min & 80 - 3000 ml/min	5	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2 set	yes	6	yes	no
Fusion Elite 10000		50 - 5000 ml/ min and 100-10000 ml/min	5	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2 set	yes	6	yes	no
Fusion Elite 16000		80 - 8000 ml/ min and 160-16000 ml/min	5	2 + 4	3x3	3	yes for each each column	yes for each column	3 set	2 set	yes	6	yes	no

Sepragen, the original inventors of radial flow chromatography, is dedicated to supplying powerful, innovative tools and technologies which enable our customers to develop and manufacture life-saving biological drugs, vaccines and diagnostics quickly and cost-effectively.

©2025 - Sepragen Corporation - All right reserved

Products

Navigation

Contacts

info@sepragen.com
1-510-475-0650
Sepragen Corporation
33470 Western Avenue
Union City, California 94587