Enabling Biological Drugs Scale Up & Production
Sepragen’s products or tools are used to manufacture over 12 FDA approved drugs including Kogenate®, Alphanate®, Neupogen®, and GammaGrand®* along with a multitude of other drugs currently in clinical trials. Sepragen’s customers range from manufacturers of recombinant biological protein and peptides, vaccines manufacturers, derivates, genetic therapy vectors, monoclonal antibody producers for diagnostic and therapeutic use and enzyme producers. Our international list of customers on four continents includes a combination of big pharma and more entrepreneurial biotech companies: Amgen, Bayer, Grifols, Chiron, Cohesion, Burroughs Wellcome, Eli Lilly, Baxter, Asahi Glass, Aventis, Merck, Human Genome Sciences, CSL, Smithkline Beecham, Chugai, Schering Plough, IDEC, Hoffman La Roche, Roche Molecular Systems, Genencor, Berlex, Dade, Yoshitomi.
In one instance, over 40,000 liters of human plasma is being treated every 6 hours on 2,800 liters of Sepragen columns to produce tens of kilograms of an injectable protein drug.